Analyte-substitute reagent for use in specific binding assay methods, devices and kits

U.S. Patent Number: 5340748

Abstract: Assay reagents, devices, methods and kits used in the analysis of low molecular weight analytes which by themselves are too small or unable to bind to two specific binding members at the same time. The invention involves the use of an analyte-substitute reagent (ASR) comprising at least two components, the first of which is identical to or an analog of the analyte to be determined, while the second is an unrelated ligand for which an antibody or other specific binding member can be obtained or produced.

Inventors: Baugher; Bennett W. (Waukegan, IL), Chamberlain; Aurora J. (Buffalo Grove, IL), Devereaux; Sharon M. (Gurnee, IL), Ungemach; Frank S. (Lake Villa, IL)

Assignee: Abbott Laboratories (Abbott Park, IL)

Application Number: 08/067,254

Issued: 1994-08-23

Expired: 2006-08-23

Classes: 436/518 ; 435/7.93; 435/971; 435/973; 435/975; 436/514; 436/538; 436/540; 436/816; 436/817; 436/822

Field of search: 436/514,518,537,538,540,816,822,817,539,541 435/7.92,7.93,971,973,975

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