Azabicyclo and azacyclo oxime and amine cholinergic agents and methods of treatment

U.S. Patent Number: 5346911

Abstract: Pharmaceutically useful nitrogen containing cyclic oxime and amine substituted compounds which are azabicyclo[2.2.1]oximes, azabicyclo[2.2.2]oximes, azabicyclo[2.2.1]amines, azabicyclo[2.2.2]amines, azabicyclo[3.2.1]oximes, and amine containing heterocyclic oximes wherein the heterocyclic ring contains from 3 to 7 carbon atoms are disclosed.

Inventors: Augelli-Szafran; Corinne E. (Ypsilanti, MI), Barrett; Stephen D. (Ferndale, MI), Caprathe; Bradley W. (Redford, MI), Galan; Adam A. (Ann Arbor, MI), Jaen; Juan C. (Plymouth, MI), Lauffer; David J. (Stow, MA), Moos; Walter H. (Oakland, CA), Pavia; Michael R. (Newton, MA), Sanders; Kathryn B. (Tecumseh, MI), Tecle; Haile (Ann Arbor, MI), Thomas; Anthony J. (Ann Arbor, MI)

Assignee: Warner-Lambert Company (Morris Plains, NJ)

Application Number: 08/110,904

Issued: 1994-09-13

Expired: 2006-09-13

Classes: 514/339 ; 514/413; 546/133; 546/137; 546/200; 546/208; 546/276.7; 546/278.4; 546/279.1; 548/453

Field of search: 546/272 548/453 514/339,413

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