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1,4-dihydro-4-oxo-3-quinoline derivatives as selectively toxic mammalian antibacterial agents

U.S. Patent Number: 5385913

Abstract: Compounds of the formula ##STR1## and the pharmaceutically acceptable salts thereof, wherein Q, X and R are as defined below. The compounds of formula I are broad spectrum mammalian antibacterial agents and exhibit favorable selectivity against procaryotic cells.

Inventors: McGuirk; Paul R. (Ledyard, CT)

Assignee: Pfizer Inc. (New York, NY)

Application Number: 07/842,205

Issued: 1995-01-31

Expired: 2007-01-31

Classes: 514/312 ; 544/349; 546/156; 560/170; 560/174

Field of search: 546/156 514/312 544/349

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