HMG-COA reductase inhibitor metabolites

U.S. Patent Number: 5385932

Abstract: This invention relates to compounds of formulae I and II ##STR1## which are metabolites of tetrahydrosimvastatin and 5-hydroxy-tetrahydrosimvastatin and which are HMG--CoA reductase inhibitors.

Inventors: Vickers; Stanley (Perkasie, PA)

Assignee: Merck & Co., Inc. (Rahway, NJ)

Application Number: 07/834,948

Issued: 1995-01-31

Expired: 2007-01-31

Classes: 514/460 ; 549/292

Field of search: 549/292 514/460

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