Acylation of alcohols with Pseudomonas lipase immobilized on a polystyrene resin

U.S. Patent Number: 5387514

Abstract: The O-acylation of alcohols is carried out by reacting a vinyl ester or a carboxylic ester with Pseudomonas lipase immobilized on a hydrophobic carrier such as a polystyrene-based carrier. The polystyrene carrier preferably has a surface area of 100-1000 m.sup.2 /g, a pore volume of 25 to 75% and a pore diameter of 25-1200 .ANG.. Crosslinking may be carried out after the lipase is immobilized on the carrier.

Inventors: Schudok; Manfred (Frankfurt am Main, DE), Fulling; Gerd (Frankfurt am Main, DE), Kretzschmar; Gerhard (Eschborn, DE)

Assignee: Hoechst Aktiengesellschaft (Frankfurt am Main, DE)

Application Number: 08/173,938

Issued: 1995-02-07

Expired: 2007-02-07

Classes: 435/135 ; 435/134; 435/155; 435/180; 435/198; 435/874

Field of search: 435/134,135,155,180,198,874

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